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A liver-produced human protein produced known as Apolipoprotein A5 (APOA 5) helps in the metabolism and removal of triglycerides, or fat, in the blood. Found in foods such as deep pan pizza and other fast fare, triglycerides contribute to obesity as well as heart disease, diabetes, and other health problems. Researchers at the University of Cincinnati recently published information in the American Society for Biochemistry and Molecular Biology’s Journal of Lipid Research about using the protein in a drug to combat obesity and other health epidemics in the U.S. Take a moment to learn about the research as part of your weight loss education via Phentermine 37.5 mg.
Learning More About How Triglycerides Affect The Body
“We are really interested in understanding triglycerides because hypertriglyceridemia — too much fat in your blood — is a big factor leading to cardiovascular disease, diabetes, obesity and other health concerns,” explains Sean Davidson, a professor in UC’s departments of Pathology and Laboratory Medicine and Molecular Genetics, Biochemistry and Microbiology, and one of the paper’s authors. “When you have a lot of fat that is hanging around in your circulation it’s important to clear as much of it out as soon as possible.”
“APOA5 is highly involved in how fast triglycerides get taken out of your circulation,” says Davidson, who also holds a doctorate in biochemistry. “The more APOA5 you have the faster the triglyceride is removed. Everybody agrees it is an important protein but scientists don’t know much about its structure or how it does what it does. If we could figure out how it works we could come up with a drug that uses the same mechanism or trigger it to work better.”
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